Lisette began her career at the Metropolitan Opera, and has starred in various roles there, including Nannetta in FALSTAFF, Gretel in HANSEL AND GRETEL, Gilda in RIGOLETTO, and Susanna in LE NOZZE DI FIGARO. She has appeared many times with the Bayerische Staatsoper as Konstanze in DIE ENTFÜHRUNG AUS DEM SERAIL, a role she has also sung at the Opéra National de Paris. Her most performed role is Gilda in RIGOLETTO, which she has sung at the Dutch National Opera, Teatro dell'opera di Roma, Los Angeles Opera, the Metropolitan Opera, Opéra National de Paris, and the Teatro Real. In the U.K., Lisette triumphed as Norina in DON PASQUALE at Glyndebourne, and as LUCIA DI LAMMERMOOR at the Royal Opera House, Covent Garden. Other roles include Ophélie in HAMLET, Cleopatra in GIULIO CESARE, Leïla in LES PÊCHEURS DE PERLES, Marie in LA FILLE DU RÉGIMENT, Amalia in I MASNADIERI, and Violetta in LA TRAVIATA.

In the U.S., Lisette has appeared at the Met, San Francisco Opera, Los Angeles Opera, Philadelphia Opera, and the Washington National Opera, among others. Lisette's career also includes oratorio, recital, and concert repertoire. She has released two recital albums, titled Within/Without, and Aux filles du désert, and has performed recitals in New York City, Washington, DC, Los Angeles, and more. In concert she has appeared with the Philadelphia Orchestra, the Chicago Symphony, the Cincinnati Symphony Orchestra, the Concertgebouw in Amsterdam, among others. She has sung at Carnegie Hall, the Accademia Nazionale di Santa Cecilia in Rome, The Ravinia Festival, The Tanglewood Music Festival, The Chicago Bach Project, The Mostly Mozart Music Festival, and more. She has collaborated with many of the world's leading conductors, including Riccardo Muti, Yannick Nézet-Séguin, Anthony Pappano, Daniele Gatti, Fabio Luisi, Ivor Bolton, William Christie, and many more.